Papers of July 2023

There have been some huge trials released over the last month and we’ve got three brilliant papers to discuss!

First up we take a look at an RCT on video versus direct laryngoscopy for patients requiring emergency intubation with the DEVICE trial. The VL versus DL debate has been ongoing for quite some time now, so is this a final nail in the coffin for DL?

Next up we take a look at an RCT of prehospital TXA use in patients at risk of bleeding from major trauma in the PATCH trial. The results seen in the trial look at a glance to oppose those seen in CRASH-2, so is this the end of TXA in this cohort of patients?

Finally we have a great paper giving us further information on whether we should we be initiating immediate antihypertensive treatment for patients admitted to hospital with asymptomatic hypertension.

Once again we’d love to hear any thoughts or feedback either on the website or via twitter @TheResusRoom.

Simon & Rob

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References

Video versus Direct Laryngoscopy for Tracheal Intubation of Critically Ill Adults. Prekker. NEJM. 2023

Prehospital Tranexamic Acid
for Severe Trauma. The PATCH-Trauma Investigators and the ANZICS Clinical Trials Group. NEJM. 2023

Clinical Outcomes of Intensive Inpatient Blood Pressure Management in Hospitalized Older Adults. JAMA Int Med. Anderson. 2023