TXA in GI Bleeds

Tranexamic Acid (TXA) has gained a significant amount of attention over the last few years as multiple studies have shown it’s utility in decreasing haemorrhage and associated mortality. It has become part of major trauma guidelines, post part haemorrhage protocols and many have adopted it to the management of traumatic brain injury. The findings have…

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TXA time to treatment

In this episode we cover a paper that you have to know about! The use of tranexamic acid(or TXA) has become widespread in the case of major trauma and bleeding and post partum haemorrhage. This time we discuss a recent paper that asks us if giving it within 3 hours is enough, or whether we… Read More

April 2020

Here are the papers that caught our eye over the last month, many of these will go onto form the topics for our monthly podcasts and topics which you can subscribe to here. Airway Detsky ME, Jivraj N, Adhikari NK, et al. Will This Patient Be Difficult to Intubate?: The Rational Clinical Examination Systematic Review. JAMA. 2019;321(5):493–503. doi:10.1001/jama.2018.21413 Cook TM, El-Boghdadly… Read More

Crash 3

So an incredibly important paper, CRASH-3, has just been published in the Lancet, which looks at the treatment of head injuries with Tranexamic Acid (TXA). TXA has been shown to save lives in trauma patients at the risk of major haemorrhage, with the notable exclusion of those with head injuries, CRASH-2. TXA has been shown…

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Papers of October 2019

Welcome to October '19 papers podcast. You can't go far without the topic of TXA as a treatment for anything that bleeds being mentioned! With the publication of CRASH-2 and the WOMAN trial practice has crept such that administration in gastro-intestinal bleeding is seen fairly frequently. However, current guidelines don't recommend the use of TXA… Read More

Shock in Trauma

So as promised, and following on from our previous shock episode, this time we've covered the topic of shock in Trauma. It's a massive topic and one that we all, yet again, can make a huge difference for our patients' outcomes. There is some crossover as you'd expect from the concepts and assessment that we… Read More

July 2019

Here are the papers that caught our eye over the last month, many of these will go onto form the topics for our monthly podcasts and topics which you can subscribe to here. Cardiac Arrest Diagnostic and prognostic utility of cardiac troponin in post-cardiac arrest care. Agusala V. Resuscitation. 2019 How do information sources influence the reported Cerebral Performance Category (CPC)… Read More

Papers of August 2018

Welcome to August's papers of the month. So this is our last offering for the summer until whilst we take a short break until September, so we had to finish off we 3 great papers! First up we look at the drug of the moment (or decade...) in tranexamic acid and the effect that it… Read More

Papers of January 2018

Happy New Year!! Welcome back to the podcast and what we hope will be a superb year. We've got three excellent papers that are extremely relevant to our practice and will have an impact on practice. First up it's a paper looking at the benefit of iv versus oral paracetamol in the Emergency Department, something we… Read More